Sevilla defeated Barcelona 2-0 in the first leg of the Copa Del Rey quarter final.
Lionel Messi was rested while Coutinho and Suarez started from the bench.
New signing, Boateng came of the bench to make his debut for the Blaugrana but he was powerless to make anything happen.
Pablo Sarabia and Ben Yedder scored two second half goals to leave Barcelona with a mountain to climb in the second leg at the Camp Nou Stadium.
Barcelona have won the Copa Del Rey four times in a row.
Coutinho was presented with an opportunity to reduce the deficit but blasted over the bar when he could have scored.